PoreWise

One finding · Human trial · 2019

Study title

A randomized study to evaluate the efficacy and effectiveness of two sunscreen formulations on Indian skin types IV and V with pigmentation irregularities

Kind of evidence
Human trial 2019 · 216 people · enrolled / 216 completed Indian adults, Fitzpatrick IV-V · PMID 30381582
Measured outcome
Skin effect
Year
2019
Who was studied
230 enrolled / 216 completed Indian adults, Fitzpatrick IV-V
Sample size
216
Measured outcome
In 216 Indian adults with Fitzpatrick skin types IV-V and pigmentation irregularities, regular use of two commercial sunscreens over 12 weeks significantly improved the clinical density of pigmented spots, skin radiance and chromameter-measured pigmentation.
Certainty
Low
Who was measured
Indian adults with Fitzpatrick IV-V skin, solar lentigines or PIH, applying sunscreen twice daily for 12 weeks.
Study limits
Single centre; industry involvement.

Where it comes from

PMID 30381582

Skin concerns studied

Other findings on the same ingredient or concern

  1. Skin effect
    An Investigator-Blinded, Randomized Trial of a Broad-Spectrum Sunscreen Containing Sclareolide and Niacinamide for the Prevention of Post-inflammatory Hyperpigmentation in Skin of Color

    In 20 people with Fitzpatrick skin types IV-V, a broad-spectrum sunscreen containing sclareolide and niacinamide significantly prevented experimentally induced post-inflammatory hyperpigmentation: in stripped, exposed zones the protected skin improved by +5.96 ITA degrees versus -9.88 in unprotected skin (net protection about 16 ITA degrees, p < 0.001).

    Human trial · 2026 · 20 people · participants with Fitzpatrick skin types IV-V · People with darker skin phototypes (IV-V) prone to post-inflammatory hyperpigmentation, applying the sunscreen daily for 20 days under UV and visible-light exposure. · Small sample (20), within-subject controlled model of experimentally induced pigmentation; the abstract calls for comparative studies with and; industry involvement.

    PMID 41240206