Source · study Evaluation of anti-wrinkle effects of a novel cosmetic containing niacinamide Primary source Publisher:The Journal of Dermatology (Kawada A, 2008) Source type:Journal · study Last checked:2026-11-10 URL: https://doi.org/10.1111/j.1346-8138.2008.00537.x Pages that cite it Evidence: In a randomized, placebo-controlled split-face study of 30 healthy Japanese women, a cosmetic containing 4% niacinamide reduced the skin-surface average roughness (Ra) value significantly more than the niacinamide-free control site after 8 weeks (P<0.05).