Source · review Efficacy of topical vitamin C in melasma and photoaging: A systematic review Primary source Publisher:Journal of Cosmetic Dermatology (Correia G, Magina S) Source type:Journal · review Last checked:2026-10-29 URL: https://doi.org/10.1111/jocd.15748 Pages that cite it Evidence: A 2023 systematic review of 7 randomized controlled trials (139 volunteers) found that topically applied vitamin C made uneven, wrinkled skin appear smoother and lightened pigmentation on objective assessments, though noticeable change may need long-term use.