PoreWise One finding · Human trial · 2019
Study title
Topical application and oral supplementation of peptides in the improvement of skin viscoelasticity and density
- Kind of evidence
- Human trial 2019 · 60 people · healthy women aged 40-50 · PMID 30834689
- Measured outcome
- Skin effect
- Year
- 2019
- Who was studied
- 60 healthy women aged 40-50
- Sample size
- 60
- Measured outcome
- In 60 healthy women aged 40-50, a topical peptide formulation significantly increased stratum corneum water content and skin elasticity after 28 days, and affected dermis echogenicity after 90 days.
- Certainty
- Low
- Who was measured
- Healthy women aged 40-50 using a topical peptide formulation for 28 to 90 days.
- Study limits
- The study also included oral collagen groups and the conclusion emphasises complementarity.
Where it comes from
- Topical application and oral supplementation of peptides in the improvement of skin viscoelasticity and density
Published by Journal of Cosmetic Dermatology (Maia Campos PMBG, et al.) · Last checked 2026-11-10
Skin concerns studied
Other findings on the same ingredient or concern
- Skin effectCosmetic benefit of a biomimetic lamellar cream formulation on barrier function or the appearance of fine lines and wrinkles in randomized proof-of-concept clinical studies
In 72 women with visible signs of ageing, a niacinamide-containing biomimetic lamellar cream significantly improved the Cutometer R5 elasticity parameter, wrinkle score, TEWL and corneometer values over 4 weeks compared against the untreated side.
Human trial · 2019 · 72 people · women with visible signs of ageing (Study 2) · Women with visible signs of ageing, applying the cream twice daily for 4 weeks. · Grading of high-resolution images failed to detect improvements in skin texture; proof-of-concept studies.