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Skin concern

Loss of firmness

Primary source

Loss of firmness: the loss of skin tightness and elasticity that comes with ageing, as the dermis's structural proteins, collagen and elastin, change in structure and amount. It is a feature of skin ageing. The strongest evidence comes from a 2019 human trial: In 72 women with visible signs of ageing, a niacinamide-containing biomimetic lamellar cream significantly improved the Cutometer R5 elasticity parameter, wrinkle score, TEWL and corneometer values over 4 weeks compared against the untreated side. 1 ingredient has evidence for Loss of firmness: Niacinamide.

The two studies measured elasticity, wrinkle or roughness scores over weeks on small groups. Firmness sits within the broader ageing picture.

Where the definition comes from

Source wording

“Skin aging is characterized by features such as wrinkling, loss of elasticity, laxity, and rough-textured appearance … accompanied by structural and functional changes in extracellular matrix components such as collagens and elastin.” — Zhang et al., Cell Transplant 2018 (PMID 29692196).

Fighting against Skin Aging: The Way from Bench to Bedside Cell Transplantation (Zhang S)

Ingredients at a glance

2019 · 72 people · women with visible signs of ageing (Study 2) · PMID 30414275

Ingredient Measured outcome Based on Certainty Year
Niacinamide Skin effect Human trial Moderate 2019
— Skin effect Human trial Low 2019

Studies and results

  1. 1 Niacinamide Skin effect
    Cosmetic benefit of a biomimetic lamellar cream formulation on barrier function or the appearance of fine lines and wrinkles in randomized proof-of-concept clinical studies

    In 72 women with visible signs of ageing, a niacinamide-containing biomimetic lamellar cream significantly improved the Cutometer R5 elasticity parameter, wrinkle score, TEWL and corneometer values over 4 weeks compared against the untreated side.

    Human trial · 2019 · 72 people · women with visible signs of ageing (Study 2) · Women with visible signs of ageing, applying the cream twice daily for 4 weeks. · Grading of high-resolution images failed to detect improvements in skin texture; proof-of-concept studies.

    PMID 30414275

    Read the full finding →
    Source:Cosmetic benefit of a biomimetic lamellar cream formulation on barrier function or the appearance of fine lines and wrinkles in randomized proof-of-concept clinical studies

Study limits

Study conditions and measured outcomes.

  • Niacinamide Human trial · 2019

    Grading of high-resolution images failed to detect improvements in skin texture; proof-of-concept studies.

  • ev-firmness-topical-peptides Human trial · 2019

    The study also included oral collagen groups and the conclusion emphasises complementarity.

Products with a basis for this

23 products · 10% Niacinamide Booster · Acne Control Cleanser · 2019 · 72 people · women with visible signs of ageing (Study 2) · PMID 30414275

Research-backed approaches

These studies measured finished products and whole routines.

  1. 1 Skin effect
    Topical application and oral supplementation of peptides in the improvement of skin viscoelasticity and density

    In 60 healthy women aged 40-50, a topical peptide formulation significantly increased stratum corneum water content and skin elasticity after 28 days, and affected dermis echogenicity after 90 days.

    Human trial · 2019 · 60 people · healthy women aged 40-50 · Healthy women aged 40-50 using a topical peptide formulation for 28 to 90 days. · The study also included oral collagen groups and the conclusion emphasises complementarity.

    PMID 30834689

    Read the full finding →
    Source:Topical application and oral supplementation of peptides in the improvement of skin viscoelasticity and density

Common questions

Which ingredients have been studied for Loss of firmness?
Ingredients with evidence for Loss of firmness: Niacinamide.
How many people were studied?
2 findings · 2019 · 72 people · women with visible signs of ageing (Study 2) · PMID 30414275
What can I use for Loss of firmness?
Niacinamide · 2019 · 72 people · women with visible signs of ageing (Study 2) · PMID 30414275
Can I use these every day for Loss of firmness?
Women with visible signs of ageing, applying the cream twice daily for 4 weeks（2019 · 72 participants · 72 women with visible signs of ageing (Study 2) · PMID 30414275）

Other concerns

Acne marks and scars Acne and breakouts Barrier damage Blackheads Bumps and rough texture Closed comedones Combination skin Dark circles Dark spots Skincare for deeper skin tones Dehydrated skin Dryness Dull skin Eczema and atopic dermatitis Hyperpigmentation Large pores Melasma Skincare for men Oily skin Skincare while on acne medication Peeling and flaking Perioral dermatitis Skincare during pregnancy Psoriasis Facial redness Rosacea Sebaceous filaments Sensitive skin Sun damage Sun protection Teenage skin Uneven skin tone Wrinkles and fine lines