PoreWise One finding · Human trial · 2023
Study title
Efficacy of anti-sebum moisturizing cream containing 2% l-carnitine and 5% epigallocatechin gallate in seborrhea: A randomized clinical trial
- Kind of evidence
- Human trial 2023 · 90 people · subjects with seborrhea · PMID 37194909
- Measured outcome
- Skin effect
- Year
- 2023
- Who was studied
- 90 subjects with seborrhea
- Sample size
- 90
- Measured outcome
- In 90 people with seborrhea, moisturisers containing 2% L-carnitine, 5% epigallocatechin gallate, or both produced statistically significant reductions in sebum level from baseline over 4 weeks, with the EGCG and combination groups showing greater anti-sebum effects than L-carnitine alone (p = 0.009).
- Certainty
- Moderate
- Who was measured
- People with seborrhea applying an anti-sebum moisturising cream for 4 weeks.
- Study limits
- All three arms contained active ingredients; sebum was measured alongside hydration and TEWL improvements.
Where it comes from
- Efficacy of anti-sebum moisturizing cream containing 2% l-carnitine and 5% epigallocatechin gallate in seborrhea: A randomized clinical trial
Published by Journal of Cosmetic Dermatology (Detudom P, et al.) · Last checked 2026-11-10
Skin concerns studied
Other findings on the same ingredient or concern
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- Skin effectThe safety and efficacy of 3% Cannabis seeds extract cream for reduction of human cheek skin sebum and erythema content
In a 12-week single-blind, base-controlled study in healthy men, a cream containing 3% Cannabis seed extract significantly reduced cheek sebum and erythema compared with the extract-free base (p<0.05).
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- Skin effectThe effect of 2% niacinamide on facial sebum production
In a double-blind, placebo-controlled trial of 100 Japanese subjects, a 2% niacinamide moisturiser significantly lowered sebum excretion rate after 2 and 4 weeks; in a separate 30-person Caucasian split-face study it significantly reduced casual sebum level after 6 weeks.
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