PoreWise One finding · Human trial · 1987
Study title
Melasma in pregnancy: reduction of its appearance with the use of a broad-spectrum sunscreen
- Kind of evidence
- Human trial 1987 · 30 people · pregnant women with good adherence (14 sunscreen / 16 placebo), analysed from a larger enrolled cohort · PMID 3312862
- Measured outcome
- Skin effect
- Year
- 1987
- Who was studied
- 30 pregnant women with good adherence (14 sunscreen / 16 placebo), analysed from a larger enrolled cohort
- Sample size
- 30
- Measured outcome
- In a placebo-controlled trial in pregnant women, daily application of a broad-spectrum SPF 10 sunscreen to the face from the second trimester through summer significantly reduced the appearance of melasma compared with placebo among the 30 women with good adherence (14 sunscreen, 16 placebo).
- Certainty
- Moderate
- Who was measured
- Appearance of melasma during pregnancy with daily facial sunscreen use.
- Study limits
- 30 adherent participants were analysed; SPF 10 is far below current broad-spectrum recommendations; published in 1987 in a Spanish-language journal; the effect is on preventing new melasma.
Where it comes from
- Melasma in pregnancy: reduction of its appearance with the use of a broad-spectrum sunscreen
Published by Medicina Cutanea Ibero-Latinoamericana (Abarca J, 1987) · Last checked 2026-11-10
Skin concerns studied
Other findings on the same ingredient or concern
- Skin effectClinical efficacy of liposome-encapsulated Aloe vera on melasma treatment during pregnancy
In a double-blind randomized trial of 180 pregnant women with melasma in their second trimester or later, 5 weeks of liposome-encapsulated Aloe vera leaf gel extract improved MASI scores by 32% versus 10% with the non-liposomal Aloe vera gel control, with a significant between-group difference in mean MASI after treatment.
Human trial · 2017 · 180 people · pregnant women with melasma in the second trimester or later (90 per group) · Melasma Area and Severity Index (MASI) over 5 weeks in pregnant women. · The comparator is an active Aloe vera gel.