PoreWise One finding · Human trial · 1999
Study title
The effects of topical vitamin E on the cosmetic appearance of scars
- Kind of evidence
- Human trial 1999 · 15 people · Adults after surgical removal of skin cancer · PMID 10417589
- Measured outcome
- Sensitization
- Year
- 1999
- Who was studied
- Adults after surgical removal of skin cancer
- Sample size
- 15
- Measured outcome
- In the same split-scar trial, 33% of the participants developed contact dermatitis to the vitamin E ointment.
- Certainty
- Low
- Who was measured
- Vitamin E in a petrolatum-based ointment applied to healing surgical wounds, twice daily for four weeks.
- Study limits
- Small trial (15 people) with a single product.
Where it comes from
- The effects of topical vitamin E on the cosmetic appearance of scars
Published by Dermatologic Surgery (Baumann & Spencer) · Last checked 2026-10-26
Ingredients it was measured on
Other findings on the same ingredient or concern
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In 31 women aged 43-65, a serum combining vitamins C and E with green tea polyphenols produced statistically significant improvements in all clinically graded parameters over 12 weeks, including enhanced skin smoothness and radiance, plus an ultrasound-measured increase in skin density.
Human trial · 2021 · 31 people · healthy women aged 43-65 (mean 57.9) · Women aged 43-65 with photoaged facial skin, applying the serum twice daily for 12 weeks. · Radiance was a clinical grading parameter.
- Skin effectAnti-aging and brightening effects of a topical treatment containing vitamin C, vitamin E, and raspberry leaf cell culture extract: A split-face, randomized controlled trial
In a split-face randomized controlled trial of 50 women, a serum with 20% vitamin C, vitamin E and raspberry leaf cell culture extract significantly improved skin radiance measured by Glossymeter GL200, along with skin colour and elasticity, over 2 months.
Human trial · 2020 · 50 people · women aged 30-65 · Women aged 30-65 applying the serum to one side of the face for 2 months, with the untreated side as control. · Split-face with an untreated.
- Skin effectThe effects of topical vitamin E on the cosmetic appearance of scars
In a double-blind trial that split each scar into two halves. Or made worse, the cosmetic appearance.
Human trial · 1999 · 15 people · Adults after surgical removal of skin cancer · Scars after surgical removal of skin cancer, treated twice daily for four weeks with a petrolatum-based ointment. · Fifteen people, one centre, published in 1999. Pigmentation, or the job vitamin E does inside a formula, where it slows oxidation of the oils.