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Ingredient

Tocopherol

Public database

TOCOPHEROL

Tocopherol is vitamin E. Formulators add it mainly to slow oxidation of the oils in a product. The strongest evidence comes from a 2020 human trial: In a split-face randomized controlled trial of 50 women, a serum with 20% vitamin C, vitamin E and raspberry leaf cell culture extract significantly improved skin radiance measured by Glossymeter GL200, along with skin colour and elasticity, over 2 months. 2020 · 50 people · women aged 30-65 · PMID 31975502 · Split-face with an untreated. 22 products contain Tocopherol; the highest it appears is number 13 of 18.

INCI name:
TOCOPHEROL
CAS number:
59-02-9
Source:
PubChem

Functions

Products with this ingredient

Tocopherol appears on 22 product ingredient lists, most often around number 25; its highest position is number 13 of 18.

Product Brand Where it sits on the list
Squalane Cleanser The Ordinary 13 of 18
C15 Brightening Super Booster Paula's Choice 14 of 17
Daily Facial Moisturizer SPF 50 Cetaphil 14 of 22
Anthelios UVMune 400 Invisible Fluid SPF50+ (fragrance-free) La Roche-Posay 16 of 26
Hyaluronic Acid 2% + B5 The Ordinary 16 of 23
Hydrating Facial Cleanser CeraVe 19 of 24
Alpha Arbutin Serum 2% Naturium 20 of 20
Moisturizing Cream CeraVe 21 of 24
Tranexamic Topical Acid 5% Naturium 22 of 22
Daily Moisturizing Lotion CeraVe 24 of 25
Cicaplast Baume B5+ La Roche-Posay 25 of 27
SA Cream for Rough & Bumpy Skin CeraVe 25 of 29
Pure Vitamin C12 Serum La Roche-Posay 27 of 30
Mela B3 Serum La Roche-Posay 28 of 32
Skin Renewing Retinol Serum CeraVe 28 of 37
Glow Serum : Propolis + Niacinamide Beauty of Joseon 30 of 30
Hyalu B5 Suractivated Serum La Roche-Posay 30 of 32
Eye Repair Cream CeraVe 31 of 41
Revive Eye Serum : Ginseng + Retinal Beauty of Joseon 32 of 36
Deep Hydration Refreshing Eye Serum Cetaphil 33 of 35
Natural Moisturizing Factors + HA The Ordinary 35 of 46
Advanced Night Repair Eye Supercharged Gel-Creme Estée Lauder 49 of 55

Studies and results

  1. 1 Skin effect
    Anti-aging and brightening effects of a topical treatment containing vitamin C, vitamin E, and raspberry leaf cell culture extract: A split-face, randomized controlled trial

    In a split-face randomized controlled trial of 50 women, a serum with 20% vitamin C, vitamin E and raspberry leaf cell culture extract significantly improved skin radiance measured by Glossymeter GL200, along with skin colour and elasticity, over 2 months.

    Human trial · 2020 · 50 people · women aged 30-65 · Women aged 30-65 applying the serum to one side of the face for 2 months, with the untreated side as control. · Split-face with an untreated.

    PMID 31975502

  2. 2 Skin effect
    Novel Vitamin C and E and Green Tea Polyphenols Combination Serum Improves Photoaged Facial Skin

    In 31 women aged 43-65, a serum combining vitamins C and E with green tea polyphenols produced statistically significant improvements in all clinically graded parameters over 12 weeks, including enhanced skin smoothness and radiance, plus an ultrasound-measured increase in skin density.

    Human trial · 2021 · 31 people · healthy women aged 43-65 (mean 57.9) · Women aged 43-65 with photoaged facial skin, applying the serum twice daily for 12 weeks. · Radiance was a clinical grading parameter.

    PMID 34491027

  3. 3 Skin effect
    The effects of topical vitamin E on the cosmetic appearance of scars

    In a double-blind trial that split each scar into two halves. Or made worse, the cosmetic appearance.

    Human trial · 1999 · 15 people · Adults after surgical removal of skin cancer · Scars after surgical removal of skin cancer, treated twice daily for four weeks with a petrolatum-based ointment. · Fifteen people, one centre, published in 1999. Pigmentation, or the job vitamin E does inside a formula, where it slows oxidation of the oils.

    PMID 10417589

What to watch for

  1. 1 Sensitization
    The effects of topical vitamin E on the cosmetic appearance of scars

    In the same split-scar trial, 33% of the participants developed contact dermatitis to the vitamin E ointment.

    Human trial · 1999 · 15 people · Adults after surgical removal of skin cancer · Vitamin E in a petrolatum-based ointment applied to healing surgical wounds, twice daily for four weeks. · Small trial (15 people) with a single product.

    PMID 10417589

Skin concerns this ingredient has been studied for

The people in each study had that concern.

Common questions

What does Tocopherol do in skincare?
Tocopherol is vitamin E. Formulators add it mainly to slow oxidation of the oils in a product.
Where does Tocopherol sit in these formulas?
Tocopherol appears in 22 products; highest on the list is number 13 of 18, in Squalane Cleanser.
Which products contain Tocopherol?
Products that contain Tocopherol: Squalane Cleanser, C15 Brightening Super Booster, Daily Facial Moisturizer SPF 50, Anthelios UVMune 400 Invisible Fluid SPF50+ (fragrance-free), Hyaluronic Acid 2% + B5, Hydrating Facial Cleanser. Plus 16 more.
How strong is the evidence behind Tocopherol?
3 findings on Tocopherol; the strongest is a 2020 human trial of 50 women aged 30-65.
What did the study on Tocopherol measure?
2020 · 50 people · women aged 30-65 · PMID 31975502 · Split-face with an untreated.
Is there anything to watch for with Tocopherol?
Yes. One caution applies to Tocopherol, listed above.

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