Ingredient
Tocopherol
Public databaseTOCOPHEROL
Tocopherol is vitamin E. Formulators add it mainly to slow oxidation of the oils in a product. The strongest evidence comes from a 2020 human trial: In a split-face randomized controlled trial of 50 women, a serum with 20% vitamin C, vitamin E and raspberry leaf cell culture extract significantly improved skin radiance measured by Glossymeter GL200, along with skin colour and elasticity, over 2 months. 2020 · 50 people · women aged 30-65 · PMID 31975502 · Split-face with an untreated. 22 products contain Tocopherol; the highest it appears is number 13 of 18.
- INCI name:
- TOCOPHEROL
- CAS number:
- 59-02-9
- Source:
- PubChem
Functions
Products with this ingredient
Tocopherol appears on 22 product ingredient lists, most often around number 25; its highest position is number 13 of 18.
Studies and results
- 1 Skin effectAnti-aging and brightening effects of a topical treatment containing vitamin C, vitamin E, and raspberry leaf cell culture extract: A split-face, randomized controlled trial
In a split-face randomized controlled trial of 50 women, a serum with 20% vitamin C, vitamin E and raspberry leaf cell culture extract significantly improved skin radiance measured by Glossymeter GL200, along with skin colour and elasticity, over 2 months.
Human trial · 2020 · 50 people · women aged 30-65 · Women aged 30-65 applying the serum to one side of the face for 2 months, with the untreated side as control. · Split-face with an untreated.
- 2 Skin effectNovel Vitamin C and E and Green Tea Polyphenols Combination Serum Improves Photoaged Facial Skin
In 31 women aged 43-65, a serum combining vitamins C and E with green tea polyphenols produced statistically significant improvements in all clinically graded parameters over 12 weeks, including enhanced skin smoothness and radiance, plus an ultrasound-measured increase in skin density.
Human trial · 2021 · 31 people · healthy women aged 43-65 (mean 57.9) · Women aged 43-65 with photoaged facial skin, applying the serum twice daily for 12 weeks. · Radiance was a clinical grading parameter.
- 3 Skin effectThe effects of topical vitamin E on the cosmetic appearance of scars
In a double-blind trial that split each scar into two halves. Or made worse, the cosmetic appearance.
Human trial · 1999 · 15 people · Adults after surgical removal of skin cancer · Scars after surgical removal of skin cancer, treated twice daily for four weeks with a petrolatum-based ointment. · Fifteen people, one centre, published in 1999. Pigmentation, or the job vitamin E does inside a formula, where it slows oxidation of the oils.
What to watch for
- 1 SensitizationThe effects of topical vitamin E on the cosmetic appearance of scars
In the same split-scar trial, 33% of the participants developed contact dermatitis to the vitamin E ointment.
Human trial · 1999 · 15 people · Adults after surgical removal of skin cancer · Vitamin E in a petrolatum-based ointment applied to healing surgical wounds, twice daily for four weeks. · Small trial (15 people) with a single product.
Skin concerns this ingredient has been studied for
The people in each study had that concern.
Common questions
- What does Tocopherol do in skincare?
- Tocopherol is vitamin E. Formulators add it mainly to slow oxidation of the oils in a product.
- Where does Tocopherol sit in these formulas?
- Tocopherol appears in 22 products; highest on the list is number 13 of 18, in Squalane Cleanser.
- Which products contain Tocopherol?
- Products that contain Tocopherol: Squalane Cleanser, C15 Brightening Super Booster, Daily Facial Moisturizer SPF 50, Anthelios UVMune 400 Invisible Fluid SPF50+ (fragrance-free), Hyaluronic Acid 2% + B5, Hydrating Facial Cleanser. Plus 16 more.
- How strong is the evidence behind Tocopherol?
- 3 findings on Tocopherol; the strongest is a 2020 human trial of 50 women aged 30-65.
- What did the study on Tocopherol measure?
- 2020 · 50 people · women aged 30-65 · PMID 31975502 · Split-face with an untreated.
- Is there anything to watch for with Tocopherol?
- Yes. One caution applies to Tocopherol, listed above.