PoreWise One finding · Review article · 2024
Study title
Topical Application of Centella asiatica in Wound Healing: Recent Insights into Mechanisms and Clinical Efficacy
- Kind of evidence
- Review article 2024 · PMID 39458583
- Measured outcome
- Skin effect
- Year
- 2024
- Who was studied
- Sample size
- Measured outcome
- A 2024 review summarises that Centella asiatica's active compounds (asiaticoside, madecassoside, asiatic acid, madecassic acid) support collagen synthesis, moderate inflammation and provide antioxidant protection, and that clinical studies have explored topical Centella asiatica for wound healing and skin recovery.
- Certainty
- Low
- Who was measured
- Topical Centella asiatica extracts and their isolated compounds.
- Study limits
- This is a review.
Where it comes from
- Topical Application of Centella asiatica in Wound Healing: Recent Insights into Mechanisms and Clinical Efficacy
Published by Pharmaceutics (Witkowska K, Paczkowska-Walendowska M, Garbiec E, Cielecka-Piontek J) · Last checked 2026-10-29
Ingredients it was measured on
Other findings on the same ingredient or concern
- Skin effectThe Effectiveness and Safety of a Skin Care Product With Centella asiatica Leaf Extract, Ceramide NP, and Panthenol in Subjects With Sensitive Skin: A Prospective, Observational Study
In 88 women with sensitive skin, a face cream containing Centella asiatica leaf extract, ceramide NP and panthenol lowered the SS-10 symptom score by 66% at week 2 and 76% at week 4, with irritation, tautness, itching and redness all significantly reduced.
Human trial · 2025 · 88 people · women with sensitive skin · Chinese women with sensitive skin applying the cream to the whole face, followed up at day 2, weeks 1, 2 and 4. · Observational and self-controlled.
- Skin effectMoisturizer Containing Centella Asiatica Extract, Ceramide NP, and Panthenol for Erythema and Skin Barrier in Erythematotelangiectatic Rosacea: A Randomized Controlled Trial
In a randomized controlled trial of 75 patients with erythematotelangiectatic rosacea, a moisturizer containing Centella asiatica extract, ceramide NP and panthenol produced greater improvements in facial redness and barrier measures than the control group at day 28.
Human trial · 2026 · 75 people · patients with erythematotelangiectatic rosasma · Adults with erythematotelangiectatic rosacea using the combination moisturizer twice daily for 28 days, alongside oral minocycline. · Centella asiatica was one of three actives in the moisturizer; all adverse events were mild and self-limiting.