PoreWise Ingredient
Centella asiatica
Public databaseCENTELLA ASIATICA
Centella asiatica is a tropical herb (also called Cica or Gotu kola) whose extracts are used in skincare for calming the skin and supporting recovery; the active compounds include asiaticoside and madecassoside. The strongest evidence comes from a 2025 human trial: In 88 women with sensitive skin, a face cream containing Centella asiatica leaf extract, ceramide NP and panthenol lowered the SS-10 symptom score by 66% at week 2 and 76% at week 4, with irritation, tautness, itching and redness all significantly reduced. 2025 · 88 people · women with sensitive skin · PMID 40682399 · Observational and self-controlled.
- Also written as:
- Cica, Gotu kola, Asian centella
- INCI name:
- CENTELLA ASIATICA EXTRACT
- Source:
- PubChem
Functions
Studies and results
- 1 Skin effectThe Effectiveness and Safety of a Skin Care Product With Centella asiatica Leaf Extract, Ceramide NP, and Panthenol in Subjects With Sensitive Skin: A Prospective, Observational Study
In 88 women with sensitive skin, a face cream containing Centella asiatica leaf extract, ceramide NP and panthenol lowered the SS-10 symptom score by 66% at week 2 and 76% at week 4, with irritation, tautness, itching and redness all significantly reduced.
Human trial · 2025 · 88 people · women with sensitive skin · Chinese women with sensitive skin applying the cream to the whole face, followed up at day 2, weeks 1, 2 and 4. · Observational and self-controlled.
- 2 Skin effectMoisturizer Containing Centella Asiatica Extract, Ceramide NP, and Panthenol for Erythema and Skin Barrier in Erythematotelangiectatic Rosacea: A Randomized Controlled Trial
In a randomized controlled trial of 75 patients with erythematotelangiectatic rosacea, a moisturizer containing Centella asiatica extract, ceramide NP and panthenol produced greater improvements in facial redness and barrier measures than the control group at day 28.
Human trial · 2026 · 75 people · patients with erythematotelangiectatic rosasma · Adults with erythematotelangiectatic rosacea using the combination moisturizer twice daily for 28 days, alongside oral minocycline. · Centella asiatica was one of three actives in the moisturizer; all adverse events were mild and self-limiting.
- 3 Skin effectTopical Application of Centella asiatica in Wound Healing: Recent Insights into Mechanisms and Clinical Efficacy
A 2024 review summarises that Centella asiatica's active compounds (asiaticoside, madecassoside, asiatic acid, madecassic acid) support collagen synthesis, moderate inflammation and provide antioxidant protection, and that clinical studies have explored topical Centella asiatica for wound healing and skin recovery.
Review article · 2024 · Topical Centella asiatica extracts and their isolated compounds. · This is a review.
Skin concerns this ingredient has been studied for
The people in each study had that concern.
Common questions
- What does Centella asiatica do in skincare?
- Centella asiatica is a tropical herb (also called Cica or Gotu kola) whose extracts are used in skincare for calming the skin and supporting recovery; the active compounds include asiaticoside and madecassoside.
- How strong is the evidence behind Centella asiatica?
- 3 findings on Centella asiatica; the strongest is a 2025 human trial of 88 women with sensitive skin.
- What did the study on Centella asiatica measure?
- 2025 · 88 people · women with sensitive skin · PMID 40682399 · Observational and self-controlled.