PoreWise One finding · Human trial · 2015
Study title
The effect of physically applied alpha hydroxyl acids on the skin pore and comedone
- Kind of evidence
- Human trial 2015 · 23 people · healthy women (mean age 30) · PMID 26032934
- Measured outcome
- Skin effect
- Year
- 2015
- Who was studied
- 23 healthy women (mean age 30)
- Sample size
- 23
- Measured outcome
- In 23 women, a single application of a 4% alpha-hydroxy acid solution combined with negative-pressure physical action significantly reduced whitehead and blackhead counts at 1, 2 and 4 weeks, and reduced pore area and number at week 1, compared with AHA peeling alone.
- Certainty
- Low
- Who was measured
- Healthy women receiving a single in-clinic application in a randomised split-face design, assessed at 1, 2 and 4 weeks.
- Study limits
- The intervention was a single in-clinic chemical peeling plus negative-pressure physical action.
Where it comes from
- The effect of physically applied alpha hydroxyl acids on the skin pore and comedone
Published by International Journal of Cosmetic Science (Kim SJ, et al.) · Last checked 2026-11-10
Ingredients it was measured on
Skin concerns studied
Other findings on the same ingredient or concern
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- Skin effectAssessing the Value of Botanical Anti-Inflammatory Agents in an OTC Acne Treatment Regimen
In a 12-week randomized trial of 80 subjects aged 12 and over with mild-to-moderate acne, a botanical anti-inflammatory OTC skincare regimen produced significantly lower closed-comedone counts than a benzoyl peroxide comparator at week 4 (P<0.001) and week 12 (P=0.006), with fewer inflammatory lesions at week 4 (P=0.016).
Human trial · 2015 · 80 people · subjects aged 12+ with mild-to-moderate acne · Closed-comedone and inflammatory lesion counts over 12 weeks. · The comparator is an active benzoyl peroxide regimen.
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