PoreWise One finding · Human trial · 2011
Study title
Enhanced efficacy of a facial hydrating serum in subjects with normal or self-perceived dry skin
- Kind of evidence
- Human trial 2011 · 32 people · women aged 25-55 with normal or self-perceived dry facial skin · PMID 21386958
- Measured outcome
- Skin effect
- Year
- 2011
- Who was studied
- 32 women aged 25-55 with normal or self-perceived dry facial skin
- Sample size
- 32
- Measured outcome
- In a randomized, evaluator-blinded study of 32 women, adding a facial hydrating serum to a moisturizer for 2 weeks produced statistically significant improvements in investigator-graded facial dryness and skin softness compared with using the moisturizer alone (P<0.02).
- Certainty
- Low
- Who was measured
- Investigator-graded facial dryness and softness over 2 weeks.
- Study limits
- The comparator is a moisturizer alone.
Where it comes from
- Enhanced efficacy of a facial hydrating serum in subjects with normal or self-perceived dry skin
Published by Journal of Clinical and Aesthetic Dermatology (Werschler WP, 2011) · Last checked 2026-11-10
Skin concerns studied
Other findings on the same ingredient or concern
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- Skin effectThe efficacy of a bioactive moisturizer in mitigating side effects of acne therapies: a randomized, investigator-blind, split-face trial
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- Skin effectEfficacy of a moisturizing cream and facial mask for alleviating skin problems associated with medical mask use: A half-face, randomized controlled study
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- Skin effectSignificantly Enhanced Improvement in Dryness, Roughness, Fine Lines and Radiance Following Daily Use of a Novel Multi-Weight Hyaluronic Acid Plus Antioxidant Complex-Based Lotion Compared to a Single-Weight HA Plus Ceramide-Based Lotion
In a double-blind comparative study of 70 women with mild-to-moderate facial dryness, a multi-weight hyaluronic acid plus antioxidant lotion produced significantly greater improvements in clinician-graded visible dryness, roughness and fine lines over 8 weeks than a single-weight hyaluronic acid plus ceramide lotion, with improvements visible from week 2.
Human trial · 2024 · 70 people · women aged 25-65 with mild-to-moderate facial dryness and fine lines · Clinician-graded facial dryness, roughness and fine lines over 8 weeks. · Both arms used active moisturisers with SPF30; the study was funded by the product manufacturer.
- Skin effectEfficacy of Pseudo-Ceramide Absorption Into the Stratum Corneum and Effects on Transepidermal Water Loss and the Ceramide Profile: A Randomized Controlled Trial
In a randomized, single-blind controlled trial of 54 Japanese women with dry, sensitive facial skin, 4 weeks of a pseudo-ceramide-containing facial spray improved scaling score, stratum corneum water content, TEWL and corneocyte area, while a commercially available spray.
Human trial · 2025 · 54 people · Japanese women aged 20-49 with self-perceived dry sensitive skin and cheek TEWL >10 g/m2 per hour · Facial scaling score, stratum corneum water content and TEWL over 4 weeks. · Single-blind; the comparator is a commercial spray.