PoreWise Ingredient
Genistein
Public databaseGENISTEIN
Genistein is a soy-derived isoflavone used as an antioxidant. The strongest evidence comes from a 2026 human trial: In a 12-week randomized, double-blind, placebo-controlled trial of 80 men aged 45-65, a product combining genistein, bakuchiol and vitamins significantly improved cheek skin lightening, colour consistency, forehead spots and skin roughness versus placebo; most other measured parameters showed similar between-group difference. 2026 · 80 people · men aged 45-65 (40/40) · PMID 41562471 · Melanin, erythema, acne, elasticity, hydration, barrier and wrinkle parameters showed similar between-group differences; the authors describe the result as promising. Male-specific skincare trials are rare, and "for men" is largely a marketing label. 1 product contains Genistein, at number 17 of 27 on its ingredient list.
- INCI name:
- GENISTEIN
- Source:
- PubChem
Functions
Products with this ingredient
Genistein appears on 1 product ingredient lists, most often around number 17; its highest position is number 17 of 27.
| Product | Brand | Where it sits on the list |
|---|---|---|
| 10% Niacinamide Booster | Paula's Choice | 17 of 27 |
Studies and results
- 1 Skin effectA Randomized Controlled Trial of the Genistein Plus Bakuchiol and Vitamins (GEN(+)) Product for Male Facial Skin: Effects on Skin Appearance and Properties
In a 12-week randomized, double-blind, placebo-controlled trial of 80 men aged 45-65, a product combining genistein, bakuchiol and vitamins significantly improved cheek skin lightening, colour consistency, forehead spots and skin roughness versus placebo; most other measured parameters showed similar between-group difference.
Human trial · 2026 · 80 people · men aged 45-65 (40/40) · Men aged 45-65 applying the product twice daily for 12 weeks. · Melanin, erythema, acne, elasticity, hydration, barrier and wrinkle parameters showed similar between-group differences; the authors describe the result as promising. Male-specific skincare trials are rare, and "for men" is largely a marketing label.
Skin concerns this ingredient has been studied for
The people in each study had that concern.
Common questions
- What does Genistein do in skincare?
- Genistein is a soy-derived isoflavone used as an antioxidant.
- Where does Genistein sit in these formulas?
- Genistein appears in 1 product, 10% Niacinamide Booster, at number 17 of 27 on its ingredient list.
- Which products contain Genistein?
- Products that contain Genistein: 10% Niacinamide Booster.
- How strong is the evidence behind Genistein?
- Genistein has one study behind it: a 2026 human trial of 80 men aged 45-65 (40/40).
- What did the study on Genistein measure?
- 2026 · 80 people · men aged 45-65 (40/40) · PMID 41562471 · Melanin, erythema, acne, elasticity, hydration, barrier and wrinkle parameters showed similar between-group differences; the authors describe the result as promising. Male-specific skincare trials are rare, and "for men" is largely a marketing label.