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Ingredient

Phytic Acid

Public database

PHYTIC ACID

Phytic Acid is a plant-derived acid that binds metal ions; used as a chelating agent and, at higher levels, in exfoliating formulas. The strongest evidence comes from a 2011 human trial: In a double-blind, vehicle-controlled trial of 30 people with two or more solar lentigines, a serum with 10% L-ascorbic acid and 2% phytic acid lowered the pigmentation index of the treated lesions over three months while the vehicle-treated lesions stayed stable (P <= 0.003 from month 1 to month 4). Six adverse events, mostly halo depigmentation, were judged possibly related to the product. 2011 · 30 people · healthy subjects with two or more solar lentigines · PMID 22151934 · The serum combines two actives. Each person applied the product to one side of the body and the vehicle to the other. 30 people, and six halo-depigmentation events were possibly related to the product. The authors call for larger studies. 3 products contain Phytic Acid; the highest it appears is number 12 of 13.

INCI name:
PHYTIC ACID
Source:
PubChem

Products with this ingredient

Phytic Acid appears on 3 product ingredient lists, most often around number 17; its highest position is number 12 of 13.

Product Brand Where it sits on the list
15% Vitamin C + EGF Serum The Inkey List 12 of 13
Effaclar Ultra Concentrated Anti-Acne Serum La Roche-Posay 17 of 19
Omega+ Complex Moisturizer Paula's Choice 42 of 54

Studies and results

  1. 1 Skin effect
    A randomized controlled study to evaluate the depigmenting activity of L-ascorbic acid plus phytic acid-serum vs. placebo on solar lentigines

    In a double-blind, vehicle-controlled trial of 30 people with two or more solar lentigines, a serum with 10% L-ascorbic acid and 2% phytic acid lowered the pigmentation index of the treated lesions over three months while the vehicle-treated lesions stayed stable (P <= 0.003 from month 1 to month 4). Six adverse events, mostly halo depigmentation, were judged possibly related to the product.

    Human trial · 2011 · 30 people · healthy subjects with two or more solar lentigines · Pigmentation index, dermoscopic pigmentation and brightness (L*) of solar lentigines over three months, with two months of follow-up. · The serum combines two actives. Each person applied the product to one side of the body and the vehicle to the other. 30 people, and six halo-depigmentation events were possibly related to the product. The authors call for larger studies.

    PMID 22151934

Skin concerns this ingredient has been studied for

The people in each study had that concern.

Common questions

What does Phytic Acid do in skincare?
Phytic Acid is a plant-derived acid that binds metal ions; used as a chelating agent and, at higher levels, in exfoliating formulas.
Where does Phytic Acid sit in these formulas?
Phytic Acid appears in 3 products; highest on the list is number 12 of 13, in 15% Vitamin C + EGF Serum.
Which products contain Phytic Acid?
Products that contain Phytic Acid: 15% Vitamin C + EGF Serum, Effaclar Ultra Concentrated Anti-Acne Serum, Omega+ Complex Moisturizer.
How strong is the evidence behind Phytic Acid?
Phytic Acid has one study behind it: a 2011 human trial of 30 healthy subjects with two or more solar lentigines.
What did the study on Phytic Acid measure?
2011 · 30 people · healthy subjects with two or more solar lentigines · PMID 22151934 · The serum combines two actives. Each person applied the product to one side of the body and the vehicle to the other. 30 people, and six halo-depigmentation events were possibly related to the product. The authors call for larger studies.

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