The Ordinary AHA 30% + BHA 2% Peeling Solution vs The Ordinary Salicylic Acid 2% Solution

The Ordinary AHA 30% + BHA 2% Peeling Solution

• Glycolic acid Skin effect
  Comparative study of buffered 50% glycolic acid (pH 3.0) + 0.5% salicylic acid solution vs Jessner's solution in patients with acne vulgaris

  In a prospective, randomized, evaluator-blind, split-face trial of 20 patients with acne vulgaris, two 50% glycolic acid + 0.5% salicylic acid peels significantly reduced total lesion count (P<0.001) and produced fewer side effects than Jessner's solution.

  Human trial · 2018 · 20 people · patients with acne vulgaris · Patients with acne vulgaris receiving two 50% glycolic acid + 0.5% salicylic acid peels 2 weeks apart (one side vs Jessner's solution on the other). · Small sample (20) and a combination peel (glycolic + salicylic acid); this is a procedural peel.

  PMID 29164826

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  Source:Comparative study of buffered 50% glycolic acid (pH 3.0) + 0.5% salicylic acid solution vs Jessner's solution in patients with acne vulgaris
• Glycolic acid Skin effect
  Shake-Induced Temporary Ion-Pairing Between Lecithin and Glycolic Acid for Enhanced Exfoliation in a Novel Biphasic Serum: Comparative Ex Vivo and in Vivo Randomised Studies

  In a 2-week double-blind split-face study of 37 participants, a biphasic serum with 10% glycolic acid delivered 45.52% greater exfoliation (p<0.001) and improved skin brightness, texture and hydration versus the comparison side.

  Human trial · 2026 · 37 people · participants in a split-face study · Healthy participants using a 10% glycolic acid biphasic serum on one side of the face for 2 weeks. · Short duration (2 weeks) and a single product formulation; the study measured exfoliation and cosmetic parameters.

  PMID 41987370

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  Source:Shake-Induced Temporary Ion-Pairing Between Lecithin and Glycolic Acid for Enhanced Exfoliation in a Novel Biphasic Serum: Comparative Ex Vivo and in Vivo Randomised Studies
• PANTHENOL Skin effect
  The Effectiveness and Safety of a Skin Care Product With Centella asiatica Leaf Extract, Ceramide NP, and Panthenol in Subjects With Sensitive Skin: A Prospective, Observational Study

  In 88 women with sensitive skin, a face cream containing Centella asiatica leaf extract, ceramide NP and panthenol lowered the SS-10 symptom score by 66% at week 2 and 76% at week 4, with irritation, tautness, itching and redness all significantly reduced.

  Human trial · 2025 · 88 people · women with sensitive skin · Chinese women with sensitive skin applying the cream to the whole face, followed up at day 2, weeks 1, 2 and 4. · Observational and self-controlled.

  PMID 40682399

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  Source:The Effectiveness and Safety of a Skin Care Product With Centella asiatica Leaf Extract, Ceramide NP, and Panthenol in Subjects With Sensitive Skin: A Prospective, Observational Study
• PANTHENOL Skin effect
  A cream containing linoleic acid, 5% dexpanthenol and ceramide in the treatment of atopic dermatitis

  In 38 children with atopic dermatitis, a cream containing linoleic acid, 5% dexpanthenol and ceramide improved SCORAD significantly more than a 5% urea cream after 4 weeks (P = 0.043); both groups improved from baseline.

  Human trial · 2024 · 38 people · children with atopic dermatitis (37 completed) · Children with mild-to-moderate atopic dermatitis applying the cream twice daily for 4 weeks in a randomised, double-blind, bilateral paired design. · Both interventions were non-prescription moisturisers: this is emollient / basic skin care. Small sample (37 completed); stratum corneum hydration and time to remission stayed close between groups.

  PMID 33865303

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  Source:A cream containing linoleic acid, 5% dexpanthenol and ceramide in the treatment of atopic dermatitis