Advanced Night Repair Synchronized Multi-Recovery Complex

Product description

The serum sold in Taiwan as 小棕瓶. The list opens with water, Bifida ferment lysate and PEG-8. Contains hyaluronic acid, caffeine, squalane and two dyes.

Full ingredient list

Kept exactly as the source printed it, including spelling in the original.

1. 1 WATER
2. 2 BIFIDA FERMENT LYSATE
3. 3 PEG-8
4. 4 PROPANEDIOL
5. 5 BIS-PEG-18 METHYL ETHER DIMETHYL SILANE
6. 6 METHYL GLUCETH-20
7. 7 GLYCERETH-26
8. 8 PEG-75
9. 9 BUTYLENE GLYCOL
10. 10 ADANSONIA DIGITATA SEED EXTRACT
11. 11 TRIPEPTIDE-32
12. 12 SODIUM HYALURONATE
13. 13 YEAST EXTRACT
14. 14 LACTOBACILLUS FERMENT
15. 15 COLA ACUMINATA (KOLA) SEED EXTRACT
16. 16 ANTHEMIS NOBILIS (CHAMOMILE) FLOWER EXTRACT
17. 17 HYDROLYZED ALGIN
18. 18 PANTETHINE
19. 19 CAFFEINE
20. 20 LECITHIN
21. 21 SODIUM RNA
22. 22 BISABOLOL
23. 23 SQUALANE
24. 24 GLYCERIN
25. 25 OLETH-3 PHOSPHATE
26. 26 CAPRYLYL GLYCOL
27. 27 OLETH-3
28. 28 OLETH-5
29. 29 CHOLETH-24
30. 30 HYDROGENATED LECITHIN
31. 31 JOJOBA WAX PEG-120 ESTERS
32. 32 CETETH-24
33. 33 TOCOPHERYL ACETATE
34. 34 CARBOMER
35. 35 TRIETHANOLAMINE
36. 36 TETRASODIUM EDTA
37. 37 BHT
38. 38 XANTHAN GUM
39. 39 POTASSIUM SORBATE
40. 40 DISODIUM EDTA
41. 41 PHENOXYETHANOL
42. 42 CI 14700
43. 43 CI 19140

Water\Aqua\Eau, Bifida Ferment Lysate, Peg-8, Propanediol, Bis-Peg-18 Methyl Ether Dimethyl Silane, Methyl Gluceth-20, Glycereth-26, Peg-75, Butylene Glycol, Adansonia Digitata Seed Extract, Tripeptide-32, Sodium Hyaluronate, Yeast Extract\Faex\Extrait De Levure, Lactobacillus Ferment, Cola Acuminata (Kola) Seed Extract, Anthemis Nobilis (Chamomile) Flower Extract, Hydrolyzed Algin, Pantethine, Caffeine, Lecithin, Sodium Rna, Bisabolol, Squalane, Glycerin, Oleth-3 Phosphate, Caprylyl Glycol, Oleth-3, Oleth-5, Choleth-24, Hydrogenated Lecithin, Jojoba Wax Peg-120 Esters, Ceteth-24, Tocopheryl Acetate, Carbomer, Triethanolamine, Tetrasodium Edta, Bht, Xanthan Gum, Potassium Sorbate, Disodium Edta, Phenoxyethanol, Red 4 (Ci 14700), Yellow 5 (Ci 19140)

Ingredient analysis

BIFIDA FERMENT LYSATE · Actives · BIFIDA FERMENT LYSATE · Humectants · BIS-PEG-18 METHYL ETHER DIMETHYL SILANE · Emollients

Evidence

• Skin effect Human trial Certainty: Very low Primary source

  In a single-blind trial of 11 women, an eye pad containing 3% caffeine and 1% vitamin K in an emu-oil base was worn under one eye and a water pad under the other for four weeks. Visual and instrument assessment found less wrinkle depth and lighter dark circles on the caffeine side.

  Who it applies to: Wrinkle depth and the appearance of dark circles under the eyes over four weeks, assessed visually and with a skin-testing instrument.

  Study limits: This pad also contained 1% vitamin K and an emu-oil base. 11 women took part, the trial was single-blind, the control was a water pad. Wrinkle reduction was the main aim; dark circles were assessed alongside it.

  Source:Evaluation of the clinical efficacy and safety of an eye counter pad containing caffeine and vitamin K in emulsified Emu oil base
• Skin effect Human trial Certainty: Moderate Primary source

  All five 0.1% hyaluronic acid creams tested, from 50 kDa to 2000 kDa, raised skin hydration and overall elasticity above the vehicle cream applied to the other eye at 60 days.

  Who it applies to: 0.1% hyaluronic acid creams applied twice daily for 60 days to the eye area of women aged 30-60 with periocular wrinkles.

  Study limits: Sixty days, and the vehicle sat on the fellow eye. Hydration and elasticity were read by instruments. The volunteers were women aged 30-60 with eye-area wrinkles.

  Source:Efficacy of cream-based novel formulations of hyaluronic acid of different molecular weights in anti-wrinkle treatment
• How deep it gets In vitro study Certainty: Moderate Primary source

  Hyaluronic acid of 20-300 kDa crossed the stratum corneum in excised human skin, while hyaluronic acid of 1000-1400 kDa remained in the stratum corneum.

  Who it applies to: Excised human skin with intact stratum corneum, measured by Raman micro-imaging after topical application.

  Study limits: One laboratory's imaging study. Three molecular-weight grades were tested. "remains above" describes intact stratum corneum in this ex vivo setup.

  Source:Human skin penetration of hyaluronic acid of different molecular weights as probed by Raman spectroscopy
• Skin effect Brand claim Certainty: Moderate Public database

  Hyaluronic acid and its salt bind water at the skin surface, giving a plumper look immediately after application.

  Who it applies to: Leave-on hydrating products.

  Study limits: The effect is largely surface and temporary. In dry air a humectant. · Finding · Sodium hyaluronate · Hydrolyzed hyaluronic acid

  Source:Hyaluronic Acid (CeraVe ingredient page)PubChem
• Skin effect Human trial Certainty: Moderate Primary source

  In a randomized, double-blind, four-arm crossover study of 51 healthy volunteers with dry skin, an emollient containing glycerol and petrolatum raised corneometry-measured skin moisture significantly above its vehicle (P < 0.0001) over 12 hours. The authors attributed the hydration gain to the glycerol component and the lower water loss to the petrolatum component.

  Who it applies to: Corneometry (skin moisture) and transepidermal water loss over 12 hours after one application.

  Study limits: Measured on the forearms. The significant hydration result comes from the full emollient containing both glycerol and petrolatum.

  Source:Combined effects of glycerol and petrolatum in an emollient cream: A randomized, double-blind, crossover study in healthy volunteers with dry skin
• Skin effect Review article Certainty: Moderate Primary source

  Topical glycerol improves stratum corneum hydration, barrier function and skin mechanical properties. The review also reports reduced irritation response and faster wound healing, and traces the effect to aquaporin-3 transport and to glycerol's own presence in the skin.

  Who it applies to: Leave-on products. The review discusses both healthy skin and skin with dry or barrier-impaired conditions such as atopic dermatitis.

  Study limits: A narrative review. It compiles mechanisms and results from other studies.

  Source:Glycerol and the skin: holistic approach to its origin and functions
• Skin effect Official ingredient listing Certainty: High Public database

  Glycerin is classified as a humectant in cosmetic ingredient databases: its role in a formula is to hold water.

  Who it applies to: Cosmetic formulas generally. · Ingredient database · GLYCERIN

  Study limits: Skin effect of to the stratum corneum comes from a separate review of the literature. · Ingredient database · GLYCERIN

  Source:PubChemCosIng — European Commission cosmetic ingredient database
• Legal limits Official legal text Certainty: High Primary source

  The EU Scientific Committee on Consumer Safety concluded in 2016 that 2-phenoxyethanol is safe as a preservative at a maximum of 1.0%, which is the limit already set in Annex V/29 of the EU Cosmetics Regulation. It estimated a margin of safety of about 50 for children.

  Who it applies to: Phenoxyethanol used as a preservative in cosmetic products, at or below 1.0%.

  Study limits: The dossier behind the conclusion was submitted by Cosmetics Europe, the industry association, and the committee lowered the default toxicokinetic factor from 4.0 to 1.0 on its way to the 1.0% conclusion. The final opinion kept 1.0%.

  Source:Opinion of the Scientific Committee on Consumer Safety (SCCS) - Final version of the opinion on Phenoxyethanol in cosmetic products

Related skin concerns

Skin concerns with evidence for ingredients on this list.

Formula history

1 version of this formula on record.

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