PoreWise Ingredient
Sodium hyaluronate
Public databaseSODIUM HYALURONATE
Sodium hyaluronate is the sodium salt form of hyaluronic acid — the form most often printed on an ingredient list. The strongest evidence comes from a 2011 human trial of 76 women aged 30-60 with periocular wrinkles: All five 0.1% hyaluronic acid creams tested, from 50 kDa to 2000 kDa, raised skin hydration and overall elasticity above the vehicle cream applied to the other eye at 60 days. 2011 · 76 people · Women aged 30-60 with periocular wrinkles · PMID 22052267 · Sixty days, and the vehicle sat on the fellow eye. Hydration and elasticity were read by instruments. The volunteers were women aged 30-60 with eye-area wrinkles. 34 products contain Sodium hyaluronate; the highest it appears is number 2 of 23.
- INCI name:
- SODIUM HYALURONATE
- CAS number:
- 9067-32-7
- Source:
- PubChem
Functions
Other forms of the same substance
The same substance under other INCI names, with the product count for each.
Hyaluronic acid
the acid form of the hyaluronan polymer — a chain of glucuronic acid and N-acetylglucosamine units — and, on an ingredient list, a separate INCI name from its sodium salt.
4 products
Hydrolyzed hyaluronic acid
hyaluronic acid broken into shorter chains — the INCI name for the low-molecular-weight grade.
13 products
Products with this ingredient
Sodium hyaluronate appears on 34 product ingredient lists, most often around number 16; its highest position is number 2 of 23.
Studies and results
- 1 Skin effectEfficacy of cream-based novel formulations of hyaluronic acid of different molecular weights in anti-wrinkle treatment
All five 0.1% hyaluronic acid creams tested, from 50 kDa to 2000 kDa, raised skin hydration and overall elasticity above the vehicle cream applied to the other eye at 60 days.
Human trial · 2011 · 76 people · Women aged 30-60 with periocular wrinkles · 0.1% hyaluronic acid creams applied twice daily for 60 days to the eye area of women aged 30-60 with periocular wrinkles. · Sixty days, and the vehicle sat on the fellow eye. Hydration and elasticity were read by instruments. The volunteers were women aged 30-60 with eye-area wrinkles.
- 2 How deep it getsHuman skin penetration of hyaluronic acid of different molecular weights as probed by Raman spectroscopy
Hyaluronic acid of 20-300 kDa crossed the stratum corneum in excised human skin, while hyaluronic acid of 1000-1400 kDa remained in the stratum corneum.
In vitro study · 2016 · Excised human skin sections · Excised human skin with intact stratum corneum, measured by Raman micro-imaging after topical application. · One laboratory's imaging study. Three molecular-weight grades were tested. "remains above" describes intact stratum corneum in this ex vivo setup.
- 3 Skin effectHyaluronic Acid (CeraVe ingredient page)
Hyaluronic acid and its salt bind water at the skin surface, giving a plumper look immediately after application.
Brand claim · Leave-on hydrating products. · The effect is largely surface and temporary. In dry air a humectant. · Finding · Sodium hyaluronate · Hydrolyzed hyaluronic acid
Skin concerns this ingredient has been studied for
The people in each study had that concern.
Common questions
- What does Sodium hyaluronate do in skincare?
- Sodium hyaluronate is the sodium salt form of hyaluronic acid — the form most often printed on an ingredient list.
- Is Sodium hyaluronate the same as Hyaluronic acid and Hydrolyzed hyaluronic acid?
- Hyaluronic acid and Hydrolyzed hyaluronic acid and Sodium hyaluronate are the same substance under different INCI names: one polymer, differing by salt form and chain length. Ingredient lists print the name matching the material used in that formula.
- Where does Sodium hyaluronate sit in these formulas?
- Sodium hyaluronate appears in 34 products; highest on the list is number 2 of 23, in Hyaluronic Acid 2% + B5.
- Which products contain Sodium hyaluronate?
- Products that contain Sodium hyaluronate: Hyaluronic Acid 2% + B5, Hyaluronic Acid Booster, Alpha Arbutin Serum 2%, Beta Hydroxy Acid Serum, Hydrating Hyaluronic Acid Serum, 10% Niacinamide Booster. Plus 28 more.
- How strong is the evidence behind Sodium hyaluronate?
- 3 findings on Sodium hyaluronate; the strongest is a 2011 human trial of 76 women aged 30-60 with periocular wrinkles.
- What did the study on Sodium hyaluronate measure?
- 2011 · 76 people · Women aged 30-60 with periocular wrinkles · PMID 22052267 · Sixty days, and the vehicle sat on the fellow eye. Hydration and elasticity were read by instruments. The volunteers were women aged 30-60 with eye-area wrinkles.