PoreWise Anua · Toners
Heartleaf 77% Soothing Toner
Product
- Brand:
- Anua
- Product type:
- Toners
- Last checked:
- 2026-10-30
- Formula version:
- Pack label · 2026-10-30
- Fragrance & alcohol:
- Fragrance-free · Alcohol-free
24 ingredients on this list · Houttuynia (fish mint) distillate at number 1 · WATER at number 2 · 1,2-HEXANEDIOL at number 3
Product description
A toner with 77% heartleaf (Houttuynia Cordata) water for soothing.
Full ingredient list
Kept exactly as the source printed it, including spelling in the original.
- 1 HOUTTUYNIA CORDATA FLOWER/LEAF/STEM WATER
- 2 WATER
- 3 1,2-HEXANEDIOL
- 4 GLYCERIN
- 5 BETAINE
- 6 BUTYLENE GLYCOL
- 7 ISOPENTYLDIOL
- 8 PANTHENOL
- 9 ACRYLATES/C10-30 ALKYL ACRYLATE CROSSPOLYMER
- 10 DISODIUM EDTA
- 11 TROMETHAMINE
- 12 CENTELLA ASIATICA EXTRACT
- 13 ARCTIUM LAPPA ROOT EXTRACT
- 14 PHELLINUS LINTEUS EXTRACT
- 15 PORTULACA OLERACEA EXTRACT
- 16 CHAMOMILLA RECUTITA (MATRICARIA) FLOWER EXTRACT
- 17 VITEX AGNUS-CASTUS EXTRACT
- 18 SODIUM HYALURONATE
- 19 HYDROXYPROPYLTRIMONIUM HYALURONATE
- 20 HYDROLYZED HYALURONIC ACID
- 21 SODIUM ACETYLATED HYALURONATE
- 22 HYALURONIC ACID
- 23 SODIUM HYALURONATE CROSSPOLYMER
- 24 POTASSIUM HYALURONATE
Original label text
Houttuynia Cordata Flower/Leaf/Stem Water, Water, 1,2-Hexanediol, Glycerin, Betaine, Butylene Glycol, Isopentyldiol, Panthenol, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Disodium EDTA, Tromethamine, Centella Asiatica Extract, Arctium Lappa Root Extract, Phellinus Linteus Extract, Portulaca Oleracea Extract, Chamomilla Recutita (Matricaria) Flower Extract, Vitex Agnus-Castus Extract, Sodium Hyaluronate, Hydroxypropyltrimonium Hyaluronate, Hydrolyzed Hyaluronic Acid, Sodium Acetylated Hyaluronate, Hyaluronic Acid, Sodium Hyaluronate Crosspolymer, Potassium Hyaluronate
Ingredient analysis
GLYCERIN · Humectants · Houttuynia (fish mint) distillate · Soothing agents · DISODIUM EDTA · Chelating agents
Humectants
11Bind water and draw it into the upper layers of the skin.
Soothing agents
5Used to reduce the sensation of irritation or discomfort.
Other
5Use on the ingredient list: see the product ingredient list.
Evidence
- Skin effect Human trial Certainty: Moderate Primary source
In a randomized, double-blind, four-arm crossover study of 51 healthy volunteers with dry skin, an emollient containing glycerol and petrolatum raised corneometry-measured skin moisture significantly above its vehicle (P < 0.0001) over 12 hours. The authors attributed the hydration gain to the glycerol component and the lower water loss to the petrolatum component.
Who it applies to: Corneometry (skin moisture) and transepidermal water loss over 12 hours after one application.
Study limits: Measured on the forearms. The significant hydration result comes from the full emollient containing both glycerol and petrolatum.
- Skin effect Review article Certainty: Moderate Primary source
Topical glycerol improves stratum corneum hydration, barrier function and skin mechanical properties. The review also reports reduced irritation response and faster wound healing, and traces the effect to aquaporin-3 transport and to glycerol's own presence in the skin.
Who it applies to: Leave-on products. The review discusses both healthy skin and skin with dry or barrier-impaired conditions such as atopic dermatitis.
Study limits: A narrative review. It compiles mechanisms and results from other studies.
- Skin effect Official ingredient listing Certainty: High Public database
Glycerin is classified as a humectant in cosmetic ingredient databases: its role in a formula is to hold water.
Who it applies to: Cosmetic formulas generally. · Ingredient database · GLYCERIN
Study limits: Skin effect of to the stratum corneum comes from a separate review of the literature. · Ingredient database · GLYCERIN
- Skin effect Human trial Certainty: Moderate Primary source
In 88 women with sensitive skin, a face cream containing Centella asiatica leaf extract, ceramide NP and panthenol lowered the SS-10 symptom score by 66% at week 2 and 76% at week 4, with irritation, tautness, itching and redness all significantly reduced.
Who it applies to: Chinese women with sensitive skin applying the cream to the whole face, followed up at day 2, weeks 1, 2 and 4.
Study limits: Observational and self-controlled.
- Skin effect Human trial Certainty: Moderate Primary source
In 38 children with atopic dermatitis, a cream containing linoleic acid, 5% dexpanthenol and ceramide improved SCORAD significantly more than a 5% urea cream after 4 weeks (P = 0.043); both groups improved from baseline.
Who it applies to: Children with mild-to-moderate atopic dermatitis applying the cream twice daily for 4 weeks in a randomised, double-blind, bilateral paired design.
Study limits: Both interventions were non-prescription moisturisers: this is emollient / basic skin care. Small sample (37 completed); stratum corneum hydration and time to remission stayed close between groups.
- Skin effect Human trial Certainty: Moderate Primary source
In 110 people with facial sensitive skin, a cream containing panthenol used twice daily for 28 days significantly increased stratum corneum moisture and reduced erythema index, redness (a* value) and transepidermal water loss.
Who it applies to: People with facial sensitive skin applying the cream twice daily for 28 days.
Study limits: Panthenol was combined with prebiotics and a probiotic lysate.
- Skin effect Human trial Certainty: Low Primary source
After facial non-ablative fractional laser treatment, a panthenol mask lowered the erythema and pigmentation indices on days 3, 7 and 14 against a saline dressing, raised stratum corneum moisture, and reduced transepidermal water loss over the same days. Sebum content was also higher in the mask group on days 7 and 14.
Who it applies to: Skin recovering from 1550 nm and 1927 nm non-ablative fractional laser on the face. Both groups received standard post-procedure care.
Study limits: The mask also contained madecassoside and bisabolol. It is one trial of 60 people, all recovering from the same procedure, and the published grant list includes L'Oreal Dermatological Beauty China (La Roche-Posay).
- Skin effect Human trial Certainty: Low Primary source
In a randomized, investigator-blind, split-face trial of 40 Asian acne patients, a moisturizer containing 4-t-butylcyclohexanol, licochalcone A, ceramide and panthenol improved facial hydration more than a traditional moisturizer (p=0.001) and produced lower dryness scores (p=0.021) over 4 weeks.
Who it applies to: Facial hydration and investigator-rated dryness over 4 weeks.
Study limits: All participants were on prescription acne therapy (including oral isotretinoin), so the dryness is drug-induced; both sides used a moisturizer, so this is a comparison between two moisturisers; acne lesion counts decreased equally on both sides.
- Sensitization Review article Certainty: Low Primary source
Panthenol is treated as non-allergenic, this review argues that frequent exposure, especially on damaged skin, can produce hypersensitivity to it. The likely route is a delayed (type IV) contact reaction; immediate and mixed reactions remain possible. Proposes patch testing with the patient's own product and with panthenol 5% in petrolatum.
Who it applies to: People who use panthenol products repeatedly, particularly those with atopic or damaged skin - the group the author says is most exposed.
Study limits: A single-author narrative review. The mechanism it proposes is stated as likely. Read it as a reason to keep panthenol on the list of possible allergens.
- Skin effect Human trial Certainty: Moderate Primary source
All five 0.1% hyaluronic acid creams tested, from 50 kDa to 2000 kDa, raised skin hydration and overall elasticity above the vehicle cream applied to the other eye at 60 days.
Who it applies to: 0.1% hyaluronic acid creams applied twice daily for 60 days to the eye area of women aged 30-60 with periocular wrinkles.
Study limits: Sixty days, and the vehicle sat on the fellow eye. Hydration and elasticity were read by instruments. The volunteers were women aged 30-60 with eye-area wrinkles.
- How deep it gets In vitro study Certainty: Moderate Primary source
Hyaluronic acid of 20-300 kDa crossed the stratum corneum in excised human skin, while hyaluronic acid of 1000-1400 kDa remained in the stratum corneum.
Who it applies to: Excised human skin with intact stratum corneum, measured by Raman micro-imaging after topical application.
Study limits: One laboratory's imaging study. Three molecular-weight grades were tested. "remains above" describes intact stratum corneum in this ex vivo setup.
- Skin effect Brand claim Certainty: Moderate Public database
Hyaluronic acid and its salt bind water at the skin surface, giving a plumper look immediately after application.
Who it applies to: Leave-on hydrating products.
Study limits: The effect is largely surface and temporary. In dry air a humectant. · Finding · Sodium hyaluronate · Hydrolyzed hyaluronic acid
- Skin effect Human trial Certainty: Low Primary source
Eight weeks of a low-molecular-weight "nano" hyaluronic acid lotion, serum and cream reduced measured periorbital wrinkle depth by up to 40% and raised corneometer hydration by up to 96%.
Who it applies to: A three-step regimen (lotion, serum, cream) built on a low-molecular-weight hyaluronic acid, used for eight weeks on women with a mean age of 45.2.
Study limits: The percentages are within-group changes. 33 participants in one centre, and the material is described as "nano" hyaluronic acid.
- How deep it gets In vitro study Certainty: Low Primary source
In reconstituted human epidermis, hyaluronic acid of about 50 kDa penetrated better than the larger grades and increased expression of genes and proteins involved in tight-junction formation and keratinocyte cohesion; its TNF-α expression stayed close from the 20 kDa grade.
Who it applies to: Reconstituted human epidermis incubated with hyaluronic acid of 20, 50, 130, 300, 800 and 1500 kDa.
Study limits: The material tested is a defined ~50 kDa grade.
- Skin effect Human trial Certainty: Moderate Primary source
Periocular wrinkle depth improved against vehicle with the 50 kDa and 130 kDa hyaluronic acid creams; after 60 days the 300, 800 and 2000 kDa creams matched vehicle on measured roughness.
Who it applies to: Replica-based roughness measurement (mean roughness Ra, maximum roughness Rz) of periocular wrinkles, with 0.1% creams applied twice daily for 60 days.
Study limits: Wrinkle depth was an instrumental secondary measure on women who already had periocular lines. The trial stopped at 60 days. The five creams differed in molecular weight, shared a base formula.
- Skin effect Human trial Certainty: Moderate Primary source
In a double-blind comparative study of 70 women with mild-to-moderate facial dryness, a multi-weight hyaluronic acid plus antioxidant lotion produced significantly greater improvements in clinician-graded visible dryness, roughness and fine lines over 8 weeks than a single-weight hyaluronic acid plus ceramide lotion, with improvements visible from week 2.
Who it applies to: Clinician-graded facial dryness, roughness and fine lines over 8 weeks.
Study limits: Both arms used active moisturisers with SPF30; the study was funded by the product manufacturer.
- Skin effect Human trial Certainty: Low Primary source
In a randomized split-face controlled trial in people with rosacea-associated erythema and sensitive skin, a dermocosmetic containing mineralizing water, probiotic fractions, hyaluronic acid and niacinamide significantly improved erythema at day 15 (p<0.01) and day 30 (p<0.001), with skin erythema, tightness, dryness, hydration and TEWL improving versus the untreated side (p<=0.05).
Who it applies to: Facial erythema, tightness, dryness, hydration and TEWL over 30 days.
Study limits: The comparator is usual skin care / an untreated half-face.
Related skin concerns
Skin concerns with evidence for ingredients on this list.
Formula history
1 version of this formula on record.