Beauty of Joseon Glow Serum : Propolis + Niacinamide vs Beauty of Joseon Glow Deep Serum : Rice + Alpha-Arbutin

All five 0.1% hyaluronic acid creams tested, from 50 kDa to 2000 kDa, raised skin hydration and overall elasticity above the vehicle cream applied to the other eye at 60 days.

Human trial · 2011 · 76 people · Women aged 30-60 with periocular wrinkles · 0.1% hyaluronic acid creams applied twice daily for 60 days to the eye area of women aged 30-60 with periocular wrinkles. · Sixty days, and the vehicle sat on the fellow eye. Hydration and elasticity were read by instruments. The volunteers were women aged 30-60 with eye-area wrinkles.

PMID 22052267

A 2026 systematic review and meta-analysis pooled seven clinical studies of tea tree oil for acne (445 patients in total). Acne severity was lower with tea tree oil than with the control treatments (pooled odds ratio 0.74, 95% CI 0.63 to 0.88), adverse events were mostly local and mild, and the reviewers judged the overall risk of bias as low.

Review article · 2026 · 445 people · patients across seven clinical studies of acne · Acne severity across seven clinical studies of topical tea tree oil, the condition that most often starts in the teenage years. · The pooled result is a modest reduction in severity. The seven studies used different tea tree oil formulations and the follow-up was short; the authors call for larger trials with standardised formulas. It also reports more mild itching, dryness and stinging in some comparisons.

PMID 42098589

In a randomized, double-blind, placebo-controlled trial of 60 people with mild-to-moderate acne, 5% tea tree oil gel was 3.55 times more effective than placebo in improving total lesion counts and 5.75 times more effective in improving the acne severity index over 45 days.

Human trial · 2007 · 60 people · people with mild-to-moderate acne · Total acne lesion counts and acne severity index over 45 days. · Cochrane rates tea tree oil evidence for acne as low quality, based largely on this single 60-participant trial.

PMID 17314442

In a split-face randomized controlled trial of 50 women, a serum with 20% vitamin C, vitamin E and raspberry leaf cell culture extract significantly improved skin radiance measured by Glossymeter GL200, along with skin colour and elasticity, over 2 months.

Human trial · 2020 · 50 people · women aged 30-65 · Women aged 30-65 applying the serum to one side of the face for 2 months, with the untreated side as control. · Split-face with an untreated.

PMID 31975502

In a randomized, placebo-controlled, double-blind trial of 102 women with melasma or solar lentigo, a cream with 2.51% arbutin applied twice daily for 8 weeks lightened discolouration in 75.86% of the melasma group and 56.00% of the solar-lentigo group.

Human trial · 2015 · 102 people · women (54 study / 48 control) with melasma or solar lentigo · Women aged 26-55 with melasma or solar lentigo, applying a 2.51% arbutin cream twice daily for 8 weeks. · The active was an aqueous extract standardised to 2.51% arbutin.

PMID 26119285

In a randomized, double-blind, controlled study of 90 volunteers with melasma, the arbutin-cream arm showed a significant fall in melasma severity score from 12.65 to 10.84 over 12 weeks; two participants had mild erythema and itching that resolved after stopping the cream.

Human trial · 2019 · 90 people · volunteers with melasma · Volunteers with melasma using an arbutin cream twice daily for 12 weeks (one of three arms: herbal mixture, arbutin cream, placebo). · Small per-arm sample and a single active agent among three comparison groups; tolerability was good overall with two mild irritation events.

PMID 30980618

In 88 women with sensitive skin, a face cream containing Centella asiatica leaf extract, ceramide NP and panthenol lowered the SS-10 symptom score by 66% at week 2 and 76% at week 4, with irritation, tautness, itching and redness all significantly reduced.

Human trial · 2025 · 88 people · women with sensitive skin · Chinese women with sensitive skin applying the cream to the whole face, followed up at day 2, weeks 1, 2 and 4. · Observational and self-controlled.

PMID 40682399

In 38 children with atopic dermatitis, a cream containing linoleic acid, 5% dexpanthenol and ceramide improved SCORAD significantly more than a 5% urea cream after 4 weeks (P = 0.043); both groups improved from baseline.

Human trial · 2024 · 38 people · children with atopic dermatitis (37 completed) · Children with mild-to-moderate atopic dermatitis applying the cream twice daily for 4 weeks in a randomised, double-blind, bilateral paired design. · Both interventions were non-prescription moisturisers: this is emollient / basic skin care. Small sample (37 completed); stratum corneum hydration and time to remission stayed close between groups.

PMID 33865303